The bile duct cancer is known to be associated with low rates of resectability and poor prognosis. A retrospective clinical study of 8 cases with intrahepatic bile duct(IHD) cancer and 52 cases with extrahepatic bile duct(EHD) cancer were
diagnosed
at
the department of surgery, Maryknoll hospital from January 1989 to December 1994.
The mean age was 65 years in the IHD cancer and 60 years in the EHD cancer. The male to female ratio were 3:1 in the IHD cancer and 1.74:1 in the EHD cancer. The incidence of hepatolithiasis, and clonorchis sinensis was 37.5%, and 12.5% in the
IHD
cancer respectively, and that of cholelithiasis, clonorchis and choledochal cyst was 17.3%, 13.5%, and 1.9% in the EHD cancer, respectively. The tumor locations of the EHD cancer were 21 cases(40.0%) in upper third, 18 cases(34.0%) in middle
third,
and
13 cases(26.0%) in lower third bile duct cancer. The operative procedures of the IHD cancer were resection (42.9%), bypass(14.2%), and biopsy(42.9%), whereas those of the EHD cancer were resection (46.7%), bypass(13.3%), and external
drainage(40.0%).
The mean survival period and the cummulative 3 years survival rate(YSR) of the IHD cancer were 15.5 months and 25.0%, whereas those of the EHD cancer were 15.5 months and 9.5% in upper third, 12.4 months and 0% in middle third, and 21.1 months
and
32.2%
in lower third bile duct cancer. The mean survival period and the cummulative 3 YSR according to methods of treatment in extrahepatic bile duct cancer were 12.7 months and 0% in PTBD, 16 months and 16.7% in external drainage, 12.8 months and 0%
in
bypass, and 21.7 months and 42.9% in resection.
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